REAL INTAKE AND PROVISION WITH VITAMINS AND CALCIUM IN OSTEOPOROSIS: ASSESSMENT BY MEASURING INTAKE AND PLASMA CONCENTRATIONS

Autor: V. N. Khodyrev, O. M. Lesnyak, A. N. Martinchik, D. M. Maksimov
Jazyk: ruština
Rok vydání: 2016
Předmět:
Zdroj: Alʹmanah Kliničeskoj Mediciny, Vol 0, Iss 32, Pp 66-72 (2016)
Druh dokumentu: article
ISSN: 2072-0505
2587-9294
DOI: 10.18786/2072-0505-2014-32-66-72
Popis: Aim: To assess the providing an organism with vitamins (А, В2, С, Е), β-carotene, and calcium in osteoporosis patients by measuring their intake and plasma concentrations. Materials and methods: 108 pairs “osteoporosis patient – healthy volunteer” aged 64.29±9.73 years were formed using a “case-control” method. Real intake of vitamins and calcium was studied defining the frequency of food taking for a month using questionnaire method. Daily intake of vitamins А, В2, С, Е, β-carotene, and calcium was calculated based on the analysis of the frequency of food taking. Among the basic group, using randomized method, 60% of osteoporosis patients were selected who underwent definition of plasma levels of vitamins А, В2, С, and Е. The same study was performed in 60 control volunteers. Results: Correlation of the intake of vitamins A, C, and β-carotene with their plasma levels wasn’t noted. It may reveal an increased need in these nutrients in osteoporosis. According to the calcium intake, every osteoporosis patient can be attributed to a population category with deep insufficiency of calcium intake (less than 500 mg a day). Conclusion: The data obtained need further investigation and, first of all, in clinical and biochemical fields (enzymatic non-provision for calcium uptake, clinical manifestations of insufficient provision with nutrients). Solution of these problems would enable regulation of food intake concerning calcium uptake in osteoporosis.
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