| Autor: |
Atefeh Asadi Rizi, Parham Reisi, Nooshin Naghsh |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Advanced Biomedical Research, Vol 5, Iss 1, Pp 20-20 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2277-9175 |
| DOI: |
10.4103/2277-9175.175906 |
| Popis: |
Background: The forced treadmill running can influence the opioid contents of the brain, through both effects of exercise and the effects of stress caused by coercion. Since opioids can cause negative effects on brain functions, this study aimed to evaluate the effect of forced treadmill exercise and blocking of opioid receptors with naloxone on memory in male rats. Materials and Methods: Experimental groups were the control, the exercise, the naloxone, and the naloxone exercise. The exercise program was treadmill running at 22 m/min at 0° inclination for 50 min/day, 6 days/week, for 4 weeks. Naloxone (1 mg/kg) was injected 5 min before the treadmill running. Morris water maze and passive avoidance learning tests were used for evaluation of memory. Acquisition phase of both tests was performed before interventions, and memory was evaluated 1-day and 1-week after the last session of exercise and treatments. Results: Our data showed that forced exercise impaired performance in passive avoidance learning test (P < 0.05 and P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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