Mechanism of MRX inhibition by Rif2 at telomeres
Autor: | Florian Roisné-Hamelin, Sabrina Pobiega, Kévin Jézéquel, Simona Miron, Jordane Dépagne, Xavier Veaute, Didier Busso, Marie-Hélène Le Du, Isabelle Callebaut, Jean-Baptiste Charbonnier, Philippe Cuniasse, Sophie Zinn-Justin, Stéphane Marcand |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
Druh dokumentu: | article |
ISSN: | 2041-1723 07447728 |
DOI: | 10.1038/s41467-021-23035-w |
Popis: | Different proteins localised at telomeres ensure chromosome end stability to prevent double strand-end break recognition. Here the authors provide new insight into how in S. cerevisiae the interaction between Rif2 and Rad50 inhibits MRX functions at telomeres. |
Databáze: | Directory of Open Access Journals |
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