| Autor: |
Yi-Chang Wang, Yu-Syuan Wu, Chia-Yang Hung, Shao-An Wang, Ming-Jer Young, Tsung-I Hsu, Jan-Jong Hung |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-018-06178-1 |
| Popis: |
USP24 has previously been reported to be involved in cancer progression. Here, the authors demonstrate that USP24 stabilizes p300 and β-TrCP to increase the levels of NF-κB and histone-3 acetylation, and decrease DNMT1 and IκB levels which promotes IL-6 expression in M2 macrophages and lung cancer cells. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
