| Autor: |
Liam Gillan, Tuija Teerinen, Leena-Sisko Johansson, Maria Smolander |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Sensors International, Vol 2, Iss , Pp 100060- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2666-3511 |
| DOI: |
10.1016/j.sintl.2020.100060 |
| Popis: |
Electrografting of aryldiazonium species is useful for linkage between electrochemical transducer surface and biosensor recognition elements. However, the process proceeds uncontrollably to form branched/multilayer growth. This paper reports harnessing steric hindrance for controlled growth of aryldiazonium coupling agent during electrografting to screen-printed carbon electrode surface, which was subsequently used for linkage of CRP recognition elements to form a biosensor with greater sensitivity (32.0 ± 0.5 μA/(ng/mL) than that formed by way of uncontrolled growth (26.6. ± 5.3 μA/(ng/mL) across a highly sensitive operating range of 0.01–10 ng/mL. To the best of our knowledge, this is the first report of this approach demonstrated as a route for biosensor fabrication. This finding suggests the approach can be exploited in immunosensor assays. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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