L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast

Autor: Lena Hochrein, Leslie A. Mitchell, Karina Schulz, Katrin Messerschmidt, Bernd Mueller-Roeber
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-02208-6
Popis: The International Synthetic Yeast Sc2.0 project has built Cre recombinase sites into synthetic chromosomes, enabling rapid genome evolution. Here the authors demonstrate L-SCRaMbLE, a light-controlled recombinase tool with improved control over recombination events.
Databáze: Directory of Open Access Journals