Epidemiological burden of meningococcal disease in Brazil: A systematic literature review and database analysis

Autor: Jéssica Vespa Presa, Rodrigo Sini de Almeida, Júlia Regazzini Spinardi, Alejandro Cane
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 80, Iss , Pp 137-146 (2019)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2019.01.009
Popis: Objectives: The aim of this study was to evaluate the epidemiological profile of invasive meningococcal disease (IMD) in Brazil, the first Latin American country to introduce the group C meningococcal conjugate vaccine (included in the vaccination schedule in 2010). Methods: A systematic review was conducted, covering the years 2005–2017, to identify epidemiological information on IMD and Neisseria meningitidis carriers in Brazil. Documents from the Brazilian Ministry of Health and two public databases were analyzed to determine annual incidence rates, absolute numbers of diagnosed cases, serogroups identified, the relative distribution of cases per serogroup, and the case fatality rate (CFR). Results: Sixteen studies were selected. The incidence rate ranged from 0.88 to 5.3 cases per 100 000 inhabitants per year. According to secondary data, the annual incidence of IMD in 2015 was highest in males
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