Adamantinoma: A review of the current literature

Autor: Sarah Louise Smyth, Ather Siddiqi, Nick Athanasou, Duncan Whitwell, Hooman Soleymani majd
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Bone Oncology, Vol 41, Iss , Pp 100489- (2023)
Druh dokumentu: article
ISSN: 2212-1374
DOI: 10.1016/j.jbo.2023.100489
Popis: Adamantinoma is a rare primary low-grade malignant tumour of the appendicular skeleton most commonly found in the tibia. It has an indolent course, with local recurrences and lung metastases occurring over a protracted duration. There have been several suggestions pertaining to a vascular origin in the literature, however, histogenesis remains unclear. Currently, guidelines are not available pertaining to clinical management.This paper presents an overview of the current literature regarding this unusual malignancy. It also explores disease etiology and acknowledges the benefits and challenges of investigations pertaining to diagnosis. It recognizes a paucity of recommendations regarding appropriate surveillance and follow up. This review aims to assist clinicians in the building of a consensus opinion for optimal adamantinoma case management under current circumstances where formal guidelines do not exist.
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