Molecular basis of MHC I quality control in the peptide loading complex
Autor: | Alexander Domnick, Christian Winter, Lukas Sušac, Leon Hennecke, Mario Hensen, Nicole Zitzmann, Simon Trowitzsch, Christoph Thomas, Robert Tampé |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022) |
Druh dokumentu: | article |
ISSN: | 2041-1723 36347434 |
DOI: | 10.1038/s41467-022-32384-z |
Popis: | The immune system monitors the health status of cells by surveilling fragments of foreign molecules from invaders presented on MHC I complexes at the cell surface. Here, the authors investigate the sequence of events of MHC I assembly and quality control cycle. |
Databáze: | Directory of Open Access Journals |
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