A Comparison of the Spot Urine Protein–Creatinine Ratio with 24-h Urinary Protein for Quantification of Proteinuria: A Hospital-based Cross-sectional Study
| Autor: | Aditya Mahaseth, Bishnu Pahari, Madhav Ghimire, Sushil Rayamajhi |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Saudi Journal of Kidney Diseases and Transplantation, Vol 34, Iss 6, Pp 548-557 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1319-2442 2320-3838 |
| DOI: | 10.4103/sjkdt.sjkdt_261_22 |
| Popis: | Quantifying the amount of proteinuria is mandatory in various disease conditions. The aim of this study was to study whether the spot urine protein-creatinine ratio (P-CR) correlates well with 24-h urinary total protein (UTP). The research hypothesis was that spot urine P-CR would correlate well with 24-h UTP. This was a cross-sectional, single-center study conducted in a tertiary care hospital. The spot urinary P–CR and 24-h urinary protein were determined from 70 patients with persistent glomerular proteinuria. This study included Nepalese patients aged 2-83 years, with a mean age of 36.56 years (standard deviation: 20.78). The number of males was slightly higher than females, and the male–female ratio was 1.26:1. Hypertension was present in 44.3% of patients, diabetes was present in 20% of patients, 74.3% of patients were suffering from acute glomerulonephritis with various causes, and 12.9% of patients had chronic kidney disease. A linear relationship existed between the spot urine P–CR and the 24-h UTP, with a correlation coefficient of 0.877 (P 3.5 g/day). Random spot urine P–CR correlated well with the 24-h UTP, particularly at lower levels of protein excretion. |
| Databáze: | Directory of Open Access Journals |
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