| Autor: |
Schneider Artur, Sadhana Jonna, Menindez Maximiliano Diaz, Jeevaratnam Suren, Balistreri Lisa, Thomas Colleen, Chirila Razvan, Berianu Florentina |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Romanian Journal of Internal Medicine, Vol 62, Iss 2, Pp 210-215 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2501-062X |
| DOI: |
10.2478/rjim-2024-0005 |
| Popis: |
Hydroxychloroquine (HCQ) induced cardiotoxicity is a rare diagnosis and is often associated with chronic use of the medication. It has been shown that chronic HCQ use is associated with a drug-induced cardiomyopathy mainly driven by acquired lysosomal storage defects leading to hypertrophy and conduction abnormalities. As the only proven treatment is the discontinuation of the offending agent, prompt recognition is required to avoid further exposure to the drug and potential progression of disease. History, physical examination and advanced imaging modalities are useful diagnostic tools, but more invasive testing with an endomyocardial biopsy is required for definitive diagnosis. We present a descriptive case series of ten patients that were diagnosed with biopsy proven HCQ cardiotoxicity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
