Subarachnoid haemorrhage in pregnancy after fertilisation with egg donation: a case report and review of the literature

Autor: Noemi J. Hughes, Saeed M.S.R. Choudhury, Sidath H. Liyanage, Munawar Hussain
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Therapeutic Advances in Reproductive Health, Vol 15 (2021)
Druh dokumentu: article
ISSN: 2633-4941
26334941
DOI: 10.1177/26334941211023542
Popis: We report a rare case of in vitro fertilisation (IVF) with egg donation complicated by a subarachnoid haemorrhage (SAH). Haemostatic changes related to IVF are known to increase risk of venous thrombosis; however, less is known regarding the risk of arterial events such as cerebrovascular accidents (CVA). Matrix metalloprotease-9 (MMP-9) upregulated in IVF patients may have a role in arterial aneurysm formation, which is the most common cause of SAH. Further research is required to assess the benefit of screening for risk of CVA and the best way to manage this in the IVF population. This may have implications for the ethics of offering certain procedures such as egg donation to women with pre-existing risk factors.
Databáze: Directory of Open Access Journals