| Autor: |
Azarcon, Corrina P., Santiago, Darby E. |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
GMS Ophthalmology Cases, Vol 10, p Doc25 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2193-1496 |
| DOI: |
10.3205/oc000152 |
| Popis: |
Objective: We report three cases of preterm neonates who presented with central nervous system (CNS) and respiratory depression after inadvertent exposure to brimonidine tartrate 0.2% and timolol maleate 0.5% fixed-combination ophthalmic drops.Case descriptions: CNS and respiratory depression were observed in the three neonates within two hours of administration of brimonidine tartrate 0.2% and timolol maleate 0.5% eye drops. Respiratory support was initiated upon admission to the neonatal intensive care unit (NICU). The effects of the drug combination lasted for 24 to 48 hours.Conclusion: This case series suggests that the drug combination of brimonidine tartrate and timolol maleate causes a prolonged depression of the central nervous and respiratory systems in preterm neonates. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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