| Autor: |
KyungAh Chun, MD, PhD |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Radiology Case Reports, Vol 17, Iss 7, Pp 2460-2463 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1930-0433 |
| DOI: |
10.1016/j.radcr.2022.03.109 |
| Popis: |
Fluorine-18 N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane (18F- FP CIT) has been used for the differential diagnosis of atypical parkinsonian disorders, and Technetium 99m ethyl cysteinate dimer (99mTc- ECD) has been used for evaluation of cerebral blood flow. A 60-year-old female with a history of Huntington's disease (HD) with full mutation of cytosine-adenine-guanine (GAG) 18/43 repeats underwent early and late 18F- FP CIT positron emission tomography/computed tomography (PET/CT) and 99mTc- ECD single-photon emission computed tomography (SPECT). The 18F-FP CIT PET/CT showed decreased uptake in both basal ganglia, both frontal and parietotemporal lobes at early images, and decreased presynaptic dopamine transporter (DAT) binding in both ventral & posterior putamen at late images. 99mTc- ECD SPECT showed decreased perfusion in both basal ganglia, both frontal and temporal lobes. Early 18F- FP CIT PET/CT and 99mTc- ECD SPECT images showed similar findings in Huntington's disease. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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