| Autor: |
Felipe Masiero Salvarini, Zélia Ines Portela Lobato, Prhiscylla Sadanã Pires, Rodrigo Otávio Silveira Silva, Guilherme Guerra Alves, Pedro Lúcio Lithg Pereira, Francisco Carlos Faria Lobato |
| Jazyk: |
angličtina |
| Předmět: |
|
| Zdroj: |
Arquivos do Instituto Biológico, Vol 80, Iss 4, Pp 450-452 |
| Druh dokumentu: |
article |
| ISSN: |
1808-1657 |
| DOI: |
10.1590/S1808-16572013000400013 |
| Popis: |
The control of enterotoxemia caused by the epsilon toxin, produced by Clostridium perfringenstype D, is based on vaccination with epsilon toxoid. The potency test for this immunogen is conducted using seroneutralization in mice. Here, an in vitro test for detection of neutralizing antibodies with Madin-Darby Canine Kidney (MDCK) cells was standardized in order to study alternative methodologies for the potency test. Titers observed in the in vivo and in vitro seroneutralization tests had a correlation of 99.73%. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
