Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine

Autor: Erin S. Calipari, Arthur Godino, Emily G. Peck, Marine Salery, Nicholas L. Mervosh, Joseph A. Landry, Scott J. Russo, Yasmin L. Hurd, Eric J. Nestler, Drew D. Kiraly
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-01881-x
Popis: Cocaine addiction is accompanied by dysfunction in neural circuits related to reward, but it is unclear how these adaptations occur. Here, authors identify granulocyte-colony stimulating factor as a potent mediator of cocaine-induced adaptations, and show that it can alter the motivation for cocaine.
Databáze: Directory of Open Access Journals