On the Regulated Nuclear Transport of Incompletely Spliced mRNAs by HIV-Rev Protein: A Minimal Dynamic Model

Autor: Jeffrey J. Ishizuka, Delaney A. Soble, Tiffany Y. Chang, Enrique Peacock-López
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Mathematics, Vol 10, Iss 21, p 3922 (2022)
Druh dokumentu: article
ISSN: 2227-7390
DOI: 10.3390/math10213922
Popis: A kinetic model for the HIV-1 Rev protein is developed by drawing upon mechanistic information from the literature to formulate a set of differential equations modeling the behavior of Rev and its various associated factors over time. A set of results demonstrates the possibility of oscillations in the concentration of these factors. Finally, the results are analyzed, and future directions are discussed.
Databáze: Directory of Open Access Journals
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