Autor: |
Nir Salinas, Jacques-Philippe Colletier, Asher Moshe, Meytal Landau |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-018-05490-0 |
Popis: |
The phenol-soluble modulin PSMα3 secreted by Staphylococcus aureus forms cross-α amyloid-like fibrils. Here the authors reveal the amyloid polymorphism of PSMs by presenting the cross-β amyloid fibril structures of the biofilm-associated PSMα1 and PSMα4 and showing that truncated PSMα3 antibacterial peptides form distinct out-of-register β-sheets and a polymorph with a hexameric architecture of β-sheets. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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