Matched Pairs with Binary Outcomes

Autor: Christiana Kartsonaki, D.R. Cox
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Revstat Statistical Journal, Vol 18, Iss 5 (2020)
Druh dokumentu: article
ISSN: 1645-6726
2183-0371
DOI: 10.57805/revstat.v18i5.321
Popis: Comparison of two treatments in matched pairs is a powerful general method for improving precision. When the outcome is binary the formulation in terms of logistic comparisons leads to an analysis in which concordant pairs, that is pairs in which both members show the same outcome, are discarded. The present paper discusses a number of conceptual aspects of this including a comparison with a linear in probabilities formulation, the relation between logistic parameters in different designs and in particular some new efficiency comparisons. Some emphasis is based on new relations between estimated effects derived from different formulations and on comparative calculations of asymptotic efficiency.
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