Links between Thyroid Disorders and Glucose Homeostasis

Autor: Young Sil Eom, Jessica R. Wilson, Victor J. Bernet
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Diabetes & Metabolism Journal, Vol 46, Iss 2, Pp 239-256 (2022)
Druh dokumentu: article
ISSN: 2233-6079
2233-6087
26255774
DOI: 10.4093/dmj.2022.0013
Popis: Thyroid disorders and diabetes mellitus often coexist and are closely related. Several studies have shown a higher prevalence of thyroid disorders in patients with diabetes mellitus and vice versa. Thyroid hormone affects glucose homeostasis by impacting pancreatic β-cell development and glucose metabolism through several organs such as the liver, gastrointestinal tract, pancreas, adipose tissue, skeletal muscles, and the central nervous system. The present review discusses the effect of thyroid hormone on glucose homeostasis. We also review the relationship between thyroid disease and diabetes mellitus: type 1, type 2, and gestational diabetes, as well as guidelines for screening thyroid function with each disorder. Finally, we provide an overview of the effects of antidiabetic drugs on thyroid hormone and thyroid disorders.
Databáze: Directory of Open Access Journals