Analysis of hematological parameters in bladder cancer in early and advanced stages at Dr. Sardjito Hospital
| Autor: | Hidayu Permata Hardi, Indrawarman Soerohardjo, Ahmad Zulfan Hendri |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), Pp 3-8 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2085-4145 2527-2950 |
| DOI: | 10.20885/JKKI.Vol14.Iss1.art2 |
| Popis: | Background: Bladder cancer (BC) is the tenth most common cancer in both males and females. Early detection can improve the patient's chances of survival, giving patients with BC a good prognosis. The hematological parameter determines the number of leukocytes, hemoglobin, platelets, and Neutrophil-Lymphocyte Ratio (NLR) in the body. The presence of abnormal values on hematological parameters indicates that the patient is in poor condition. Objective: This study aims to compare hematological parameters between early-stage and advanced BC at Dr. Sardjito Hospital. Methods: This study was a retrospective cross-sectional study using patient medical records. By using the results of the anatomical pathology, pre-operative hematology evaluated the influence on the bladder cancer stage. The sample used consisted of 130 bladder cancer patients. Chi-square and regression statistical tests were used to analyze the collected data. Results: The advanced-stage group had considerably higher leukocytosis than the early-stage group (p = 0.000). Anemia predominated more in the later-stage group than in the earlier stage (p = 0.048). Additionally, the advanced-stage group experienced thrombocytosis more frequently than the early-stage group (p = 0.000). NLR was higher in the advanced compared to the early-stage group (p = 0.000). Conclusion: Patients with advanced bladder cancer were more likely to experience abnormal hematological parameters levels than those with the earliest stages of the disease. |
| Databáze: | Directory of Open Access Journals |
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