| Autor: |
Radhika Arora, Feroz Alam, Atia Zaka-ur-Rab, Veena Maheshwari, Kiran Alam, Mahboob Hasan |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of the Egyptian National Cancer Institute, Vol 35, Iss 1, Pp 1-6 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2589-0409 |
| DOI: |
10.1186/s43046-023-00200-4 |
| Popis: |
Abstract Background Clinical utility of Ki-67 immunohistochemistry (IHC) in breast cancer (BC) is mainly limited to decide for the use of chemotherapy and estimate prognosis in patients with either Ki-67 index 30%; however, lacunae still exists pertaining to its analytical validity. Neutrophilia is common in cancer with accompanying lymphocytopenia. Neutrophil to lymphocyte ratio (NLR) captures the intricate balance between pro-tumor neutrophilia and anti-tumor lymphocyte immunity. This study aimed to correlate cellular proliferation in breast cancer with NLR. Methods An observational study was carried out including 73 cases of BC; pre-treatment NLR and Ki-67 grading were performed. NLR 0.05) and molecular subtype (p > 0.05); however, NLR was found to be significantly correlated with TNM stage (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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