| Autor: |
Grace Lee, Bjorn Kluwe, Songzhu Zhao, David Kline, Divya Nedungadi, Guy N. Brock, James B. Odei, Veena Kesireddy, Neal Pohlman, Mario Sims, Valery S. Effoe, Wen-Chih Wu, Rita R. Kalyani, Gary S. Wand, Justin Echouffo-Tcheugui, Sherita H. Golden, Joshua J. Joseph |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Endocrine and Metabolic Science, Vol 11, Iss , Pp 100126- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2666-3961 |
| DOI: |
10.1016/j.endmts.2023.100126 |
| Popis: |
Objective: To analyze associations between adiposity and the renin-angiotensin-aldosterone system (RAAS) in a large African American (AA) cohort. Methods: Cross-sectional associations of adiposity (body mass index [BMI], waist circumference [WC], waist:height ratio, waist:hip ratio, leptin, adiponectin, leptin:adiponectin ratio [LAR], subcutaneous [SAT] and visceral adipose tissue [VAT], and liver attenuation [LA]) with aldosterone, plasma renin activity (renin), and aldosterone:renin ratio (ARR) were assessed in the Jackson Heart Study using adjusted linear regression models. Results: A 1-SD higher BMI was associated with a 4.8 % higher aldosterone, 9.4 % higher renin, and 5.0 % lower ARR (all p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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