No Associations between Dairy Intake and Markers of Gastrointestinal Inflammation in Healthy Adult Cohort
| Autor: | Yasmine Y. Bouzid, Elizabeth L. Chin, Sarah S. Spearman, Zeynep Alkan, Charles B. Stephensen, Danielle G. Lemay |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Nutrients, Vol 15, Iss 16, p 3504 (2023) |
| Druh dokumentu: | article |
| ISSN: | 15163504 2072-6643 |
| DOI: | 10.3390/nu15163504 |
| Popis: | Dairy products are a good source of essential nutrients and past reviews have shown associations of dairy consumption with decreased systemic inflammation. Links between dairy intake and gastrointestinal (GI) inflammation are under-investigated. Therefore, we examined associations between reported dairy intake and markers of GI inflammation in healthy adults in a cross-sectional observational study, hypothesizing a negative association with yogurt intake, suggesting a protective effect, and no associations with total dairy, fluid milk, and cheese intake. Participants completed 24-h dietary recalls and a food frequency questionnaire (FFQ) to assess recent and habitual intake, respectively. Those who also provided a stool sample (n = 295), and plasma sample (n = 348) were included in analysis. Inflammation markers from stool, including calprotectin, neopterin, and myeloperoxidase, were measured along with LPS-binding protein (LBP) from plasma. Regression models tested associations between dairy intake variables and inflammation markers with covariates: age, sex, and body mass index (BMI). As yogurt is episodically consumed, we examined differences in inflammation levels between consumers (>0 cup equivalents/day reported in recalls) and non-consumers. We found no significant associations between dairy intake and markers of GI inflammation. In this cohort of healthy adults, dairy intake was not associated with GI inflammation. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|