Bioactive Phenolic Amides from Celtis africana

Autor: Nighat Afza, Lubna Iqbal, Abdul Malik, Ghada Ahmed Fawzy, Azza Muhammed El-Shafae, Shagufta Perveen, Areej Mohammad Al-Taweel, Mehreen Latif
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Molecules, Vol 17, Iss 3, Pp 2675-2682 (2012)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules17032675
Popis: Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 1–3 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity.
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