Oxidative Stress in Brain in Amnestic Mild Cognitive Impairment

Autor:	D. Allan Butterfield
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	lipid peroxidation Abeta and oxidative stress neuronal loss key metabolic pathways involved in MCI potential therapeutic strategies for MCI Therapeutics. Pharmacology RM1-950
Zdroj:	Antioxidants, Vol 12, Iss 2, p 462 (2023)
Druh dokumentu:	article
ISSN:	2076-3921
DOI:	10.3390/antiox12020462
Popis:	Amnestic mild cognitive impairment (MCI), arguably the earliest clinical stage of Alzheimer disease (AD), is characterized by normal activities of daily living but with memory issues but no dementia. Oxidative stress, with consequent damaged key proteins and lipids, are prominent even in this early state of AD. This review article outlines oxidative stress in MCI and how this can account for neuronal loss and potential therapeutic strategies to slow progression to AD.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/25e0c33cf8694239944be26167444090 Zobrazit plný text záznamu View record in DOAJ