Third-Generation Fatty Emulsions as Part of Parenteral Feeding in Operated Cancer Patients
| Autor: | S. V. Lomidze, I. V. Nekhayev, A. V. Sytov, I. A., Klimanov, N. B. Borovkova, S. V. Yefimenko, I. S. Korotkov, A. A. Severin |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Общая реаниматология, Vol 6, Iss 3 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1813-9779 2411-7110 04848381 |
| DOI: | 10.15360/1813-9779-2010-3-82 |
| Popis: | Objective: to study the efficacy of third- versus secondary-generation fatty emulsions as part of parenteral nutrition in patients operated on for gastric cancer. Subjects and methods. Envelope randomization was used to make up two groups, each comprising 10 patients, operated on for gastric cancer in the scope of gastrectomy. A control group received parenteral nutrition having the following components: Lipofundin MST/LST 20%, (500 ml daily) + Nutriflex 48/150 (B. Braun) (1000 ml daily, 1744 kcal/day). The study group patients were given Lipoplus 20% (500 ml daily) + Nutriflex 48/150 (1000 ml daily, 1745 kcal/day). Parenteral nutrition was used on postoperative days 1 to 5. Results. Nutritional status evaluation revealed a significant increase in the concentration of total protein and albumin in the control and study group patients on postoperative day 6. The use of both second- and third-generation fatty emulsions caused a significant increase in the concentration of triglycerides on day 6 after surgery; no differences were found between the groups. On day 6 following surgery, there was a significant decrease in IL-4 in both groups (p |
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