Solar urticaria. Case report and literature review
| Autor: | María Raigoza, Yuliana Toro, Jorge Sánchez |
|---|---|
| Jazyk: | English<br />Spanish; Castilian |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Revista Alergia México, Vol 64, Iss 3, Pp 371-375 (2017) |
| Druh dokumentu: | article |
| ISSN: | 0002-5151 2448-9190 |
| DOI: | 10.29262/ram.v64i3.202 |
| Popis: | Background: Solar urticaria is a rare type of inducible urticaria characterized by wheal and erythema formation shortly after exposure to sunlight or to an artificial light source; its pathophysiology is not yet entirely understood. The treatment of choice, in addition to exposure avoidance, consists in antihistamine administration. Clinical case: This is the case of a 27-year-old woman with no personal history of allergic diseases and with a 2-year history of erythema and wheals in photo-exposed areas associated with sunlight exposure for periods longer than 10 minutes. A provocation test was carried out; she was started on fexofenadine at 4-fold the standard dose (720 mg/day). Six weeks later, a new challenge was carried out without the antihistamine being discontinued; the reaction was less severe, but she continued with erythema for the first 60 minutes post-exposure. After 3 months on high-dose antihistamines, she referred marked improvement in her quality of life and tolerance to brief sunlight exposure (for less than 15 minutes). Conclusions: Given the knowledge there is about the proposed pathophysiological mechanism for this condition, maybe individuals with solar urticaria could benefit from anti-IgE monoclonal antibody-based therapy. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|