EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZIN
| Autor: | G. E. Bril, A. V. Egorova, I. O. Bugaeva, G. V. Ponomarev |
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| Jazyk: | ruština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 2, Pp 34-37 (2017) |
| Druh dokumentu: | article |
| ISSN: | 0372-9311 2686-7613 |
| DOI: | 10.36233/0372-9311-2017-2-34-37 |
| Popis: | Aim. Study the effect of laser emission in the red spectrum on growth of methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus, as well as photodynamic effect of photosensitizer photoditazin. Materials and methods. Effect of light of semiconductor red laser (X 660 nm, 100 mW/cm2) at 30, 60, 90 and 180 J/cm2 on growth of S. aureus colonies was determined. Time of exposure - 5, 10, 15 and 30 minutes. In certain series of experiments bacterial cells were sensitized in advance by a water solution of photoditazin at a concentration of 5x 1 O'6 M. Results. Red laser emission was established to cause a pronouncec suppression of bacterial growth. This effect on standard S. aureus strain only took place during use of relatively high exposure doses (180 J/cm2). Photosensitivity of methicillin-resistan: strain turned out to be significantly higher: bacteriostatic effect of red light was noted alreadx at the dose of 60 J/cm2. Treatment of bacterial cells with photoditazin in advance significantly enhanced growth-inhibiting effect of laser light. |
| Databáze: | Directory of Open Access Journals |
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