Community-acquired Escherichia coli meningitis and spondylodiscitis in an adult patient with discoid lupus erythematosus

Autor: Francisco Vale, Vitor Laerte Pinto Junior, Maria Isabel Casella, José Poças
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: IDCases, Vol 17, Iss , Pp - (2019)
Druh dokumentu: article
ISSN: 2214-2509
DOI: 10.1016/j.idcr.2019.e00573
Popis: Acute bacterial meningitis has a high impact on adult mortality worldwide. Community-acquired Escherichia coli meningitis (CA-ECM) is a rare and poorly described condition and the available knowledge is based on low evidence research, mainly from case reports. We describe a case of CA-ECM in Portugal in an adult patient with discoid lupus erythematosus under immunomodulatory therapy. A 73-year-old woman was admitted to the emergency department with fever and altered mental status over 48 h. Cerebrospinal fluid analysis showed 185 leukocytes/μL, including 85% neutrophils, hypoglycorrhachia (less than 5 mg/dL) and elevated protein of 423 mg/dL with positive culture for Escherichia coli. She was treated with ceftriaxone. Imaging studies also demonstrated spondylodiscitis and arthritis. She responded well to antimicrobial therapy and completed the treatment as an outpatient. Keywords: Escherichia coli, Meningitis, Spondylodiscitis, Discoid lupus erythematosus
Databáze: Directory of Open Access Journals