Autor: |
Umberto Caterino, Cristiano Cesaro, Enzo Zamparelli, Flavio Cesaro, Alba Palma, Raffaella Lucci, Pasquale Imitazione, Dino Casazza, Dario Amore |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Case Reports in Oncology, Vol 14, Iss 3, Pp 1616-1620 (2021) |
Druh dokumentu: |
article |
ISSN: |
1662-6575 |
DOI: |
10.1159/000520127 |
Popis: |
Malignant pleural effusion represents a prognostic negative factor on survival conferring stage IV disease. The median of survival is 5 months and a 5-year survival of about 3%. We describe the therapeutic success obtained from different strategies in anaplastic lymphoma kinase (ALK) inhibitors in 2 young women showing malignant pleural effusion secondary to advanced ALK-rearranged lung adenocarcinoma. This report shows that for patients with EGFR mutations in advanced lung adenocarcinoma-associated malignant pleural effusion, complete response to EGFR TKI inhibitor can be observed mostly if pleural effusion and primary lung adenocarcinoma show the same EGFR mutation status. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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