Chagas disease and perceived quality of life: a cross-sectional study

Autor: Nayara Ragi Baldoni, Nayara Dornela Quintino, Claudia Di Lorenzo Oliveira, José Luiz Padilha da Silva, Ariela Mota Ferreira, Antonio Luiz Pinho Ribeiro, Ester Cerdeira Sabino, Clareci Silva Cardoso
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 56 (2023)
Druh dokumentu: article
ISSN: 1678-9849
0037-8682
DOI: 10.1590/0037-8682-0206-2023
Popis: ABSTRACT Background: Chagas disease (ChD) is a neglected tropical disease that is caused by the protozoan parasite Trypanosoma cruzi and can negatively impact quality of life (QoL). This study aimed to assess and compare QoL between individuals with and without ChD. Methods: This cross-sectional study was performed within a concurrent cohort study (REDS). The participants were derived from two blood donation centers: São Paulo capital and Montes Claros, Minas Gerais, Brazil. Participants with ChD were identified in blood donations by serological diagnosis between 2008 and 2010, and those without ChD were donors with negative serology identified during the same period. QoL was assessed using the World Health Organization Quality of Life-BREF questionnaire. Logistic regression was used to compare sociodemographic and clinical characteristics between the groups, and mean, standard deviation, and beta regression were used to compare QoL. Results: In total, 611 individuals participated in the study (328 with ChD and 283 without ChD). Participants with ChD had lower QoL in the physical (p=0.02) and psychological (p
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