Hypomethylation of serum blood clot DNA, but not plasma EDTA-blood cell pellet DNA, from vitamin B12-deficient subjects.

Autor: Eoin P Quinlivan, Krista S Crider, Jiang-Hui Zhu, David R Maneval, Ling Hao, Zhu Li, Sonja A Rasmussen, R J Berry, Lynn B Bailey
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: PLoS ONE, Vol 8, Iss 6, p e65241 (2013)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0065241
Popis: Vitamin B12, a co-factor in methyl-group transfer, is important in maintaining DNA (deoxycytidine) methylation. Using two independent assays we examined the effect of vitamin B12-deficiency (plasma vitamin B12
Databáze: Directory of Open Access Journals