Association between intracellular adenosine triphosphate content of CD4+ T lymphocytes and mortality in sepsis patients: A prospective observational study

Autor:	Ying Xian, Dan Xie, Jian Zhu, Changlong Zheng, Min Fan, Kefeng Jiang, Kouxing Zhang
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	CD4+ T lymphocytes immune function intracellular adenosine triphosphate (iATP) mortality prognosis sepsis Immunologic diseases. Allergy RC581-607
Zdroj:	Immunity, Inflammation and Disease, Vol 12, Iss 6, Pp n/a-n/a (2024)
Druh dokumentu:	article
ISSN:	2050-4527
DOI:	10.1002/iid3.1286
Popis:	Abstract Objective This study aimed to link intracellular adenosine triphosphate content in CD4+ T lymphocytes (CD4+ iATP) with sepsis patient mortality, seeking a new predictive biomarker for outcomes and enhanced management. Methods 61 sepsis patients admitted to the Intensive Care Unit between October 2021 and November 2022 were enrolled. iATP levels were gauged using whole blood CD4+ T cells stimulated with mitogen PHA‐L. Based on CD4+ iATP levels (
Databáze:	Directory of Open Access Journals
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