1,3-Dipolar Cycloadditions of N-Benzyl Furfuryl Nitrones with Electron-rich Alkenes

Autor: Tomas Tejero, Francisco L. Merchan, Sonia Anoro, Pedro Merino
Jazyk: angličtina
Rok vydání: 2000
Předmět:
Zdroj: Molecules, Vol 5, Iss 2, Pp 132-152 (2000)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/50200132
Popis: The 1,3-dipolar cycloaddition reaction of N-benzyl-C-(2-furyl)nitrones with electron-rich alkenes gives preferentially trans-substituted 3,5-disubstituted isoxazolidines (endo approach). These experimental results are in good qualitative agreement with the predicted ones by semiempirical (AM1 and PM3) and ab initio (HF/3-21G) methods.
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