Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model

Autor:	Mu Yang, Jian-Xin Dong, Lu-Bin Li, Hai-Jie Che, Jun Yong, Fu-Bo Song, Tao Wang, Jv-Wen Zhang
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Gastroenterology Research and Practice, Vol 2016 (2016)
Druh dokumentu:	article
ISSN:	1687-6121 1687-630X
DOI:	10.1155/2016/2604032
Popis:	Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postconditioning (LIPo) and remote ischemia postconditioning (RIPo) on intestinal I/R injury. We concluded that LIPo affords protection in intestinal I/R injury in a comparable fashion with RIPo by decreasing oxidative stress, neutrophil activation, and apoptosis.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/2537a3a7484640648963fc81d076adcf Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF