| Autor: |
Laura Klösges, Sophia Chikhladze, Esther A. Biesel, Stefan Fichtner-Feigl, Uwe A. Wittel |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Surgery Open Science, Vol 15, Iss , Pp 61-66 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2589-8450 |
| DOI: |
10.1016/j.sopen.2023.07.003 |
| Popis: |
Background: Histopathological confirmation of malignancy is mandatory in patients with unresectable pancreatic cancer before initiation of palliative chemotherapy. When interventional biopsy proves unsuccessful, laparoscopic or open surgical biopsies become necessary. Methods: 66 consecutive surgical biopsies of the pancreas performed at a single institution between 01/2010 and 04/2020 were analyzed retrospectively. We analyzed sensitivity of histopathological confirmation of malignancy as well as complication rates of laparoscopic and open surgical biopsies in patients with suspected advanced pancreatic cancer after unsuccessful interventional biopsies. Results: 8 complications were observed in 46 patients requiring only a pancreatic biopsy (17.4 %) while in 13 of 20 patients complications were observed when additional procedures were necessary (65 %). Major complications CD ≥ III were observed in the “biopsy +/- port” group in 4 of 46 patients and in the “biopsy + additional procedure” cohort in 9 of 20 patients (8.7 vs. 45 %, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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