| Autor: |
Arun Ramaswamy, Anton Smith Arul Gnana Dhas |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Arabian Journal of Chemistry, Vol 11, Iss 2, Pp 275-281 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1878-5352 |
| DOI: |
10.1016/j.arabjc.2014.08.007 |
| Popis: |
This paper describes the development and validation of a HPLC method for the quantitation of Emtricitabine, Tenofovir, and Efavirenz in pure form and pharmaceutical formulations. The Zorbax SB CN, (250 × 4.6 mm, 5 μm) column was used. UV detection was performed at 260 nm. The mobile phase consisted of methanol (A) and buffer at pH 4.5(B) using the gradient: 0–10 min (90% B), 10–22 min (35% B), and 22–25 min (90% B). The flow rate was 1.5 ml/min in ambient temperature. The injection volume of sample was 20 μl. The method showed to be linear (r2 > 0.999), precise (RSD |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
