Assessing taxonomic metagenome profilers with OPAL

Autor: Fernando Meyer, Andreas Bremges, Peter Belmann, Stefan Janssen, Alice C. McHardy, David Koslicki
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Genome Biology, Vol 20, Iss 1, Pp 1-10 (2019)
Druh dokumentu: article
ISSN: 1474-760X
DOI: 10.1186/s13059-019-1646-y
Popis: Abstract The explosive growth in taxonomic metagenome profiling methods over the past years has created a need for systematic comparisons using relevant performance criteria. The Open-community Profiling Assessment tooL (OPAL) implements commonly used performance metrics, including those of the first challenge of the initiative for the Critical Assessment of Metagenome Interpretation (CAMI), together with convenient visualizations. In addition, we perform in-depth performance comparisons with seven profilers on datasets of CAMI and the Human Microbiome Project. OPAL is freely available at https://github.com/CAMI-challenge/OPAL.
Databáze: Directory of Open Access Journals