GENERALIZED PERIODONTITIS AND RHEUMATOID ARTHRITIS: IMUNOLOGICAL ASPECTS OF MUTUAL AGGRAVATION

Autor: S. I. Smiyan, I. P. Mazur, I. I. Bilozetskyi
Jazyk: English<br />Russian<br />Ukrainian
Rok vydání: 2014
Předmět:
Zdroj: Patologìâ, Iss 3, Pp 16-21 (2014)
Druh dokumentu: article
ISSN: 2310-1237
2306-8027
DOI: 10.14739/2310-1237.2014.3.36552
Popis: Aim. The combination of rheumatoid arthritis and periodontitis may have an adverse prognostic significance for both diseases. Methods and results. In order to study the relationships between generalized periodontitis course and tumor necrosis factor alpha (TNF-α) level 60 patients with rheumatoid arthritis were examined. Conclusion. It was established that markers of activity and aggression of rheumatoid arthritis, such as the presence of rheumatoid factor, antibodies to cyclic citrullinated peptide and increased level of TNF-α, play a key role in the progression of periodontitis.
Databáze: Directory of Open Access Journals