| Autor: |
Kosuke Endo, Akiko Yokoi, Yasuhiko Mishima, Akihiko Tamaki, Junkichi Takemoto, Keiichi Morita, Tamaki Iwade, Yuichi Okata, Hiroaki Fukuzawa, Yuko Bitoh, Tomomi Hasegawa, Makiko Yoshida, Yoshinobu Akasaka, Hideaki Okajima, Yoshihiro Oshima, Kosaku Maeda, Shinji Uemoto |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Journal of Pediatric Surgery Case Reports, Vol 7, Iss C, Pp 20-22 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2213-5766 |
| DOI: |
10.1016/j.epsc.2016.01.004 |
| Popis: |
Hepatoblastoma with intraatrial tumor thrombus is relatively rare. We report a case of hepatoblastoma with tumor thrombus extending into the right atrium, which responded well to chemotherapy and was resected using extracorporeal circulation. A 4-year-old girl was referred to our hospital because of abdominal distention and tenderness. A computed tomography (CT) scan showed a large tumor occupying the left 3 segments of the liver with tumor thrombus extending into the right atrium. There was also a small intrahepatic metastasis in the right lobe of the liver. She was diagnosed with hepatoblastoma on the basis of the results of open biopsy. Neoadjuvant chemotherapy with an intense CDDP-based regimen was performed. The tumor responded well to chemotherapy, and intrahepatic metastasis became undetectable on CT scan, although the tumor thrombus remained in the right atrium. After 7 courses of chemotherapy, we performed resection using extracorporeal circulation. The postoperative course was uneventful, and adjuvant chemotherapy was started 10 days after the operation. Her serum alpha-fetoprotein (AFP) level decreased to the normal range, and she was free of disease for 1 year after the operation. Tumor resection using extracorporeal circulation can be performed safely and is justified in patients with intraatrial tumor thrombus. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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