| Autor: |
Chunliang Xu, Xin Gao, Qiaozhi Wei, Fumio Nakahara, Samuel E. Zimmerman, Jessica Mar, Paul S. Frenette |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-018-04726-3 |
| Popis: |
Endothelial cells (EC) are known to contribute to haematopoietic stem cell (HSC) maintenance in the bone marrow (BM). Here the authors demonstrate that arterial ECs can be distinguished from sinusoidal ECs by podoplanin and Sca-1 expression, and that specifically arterial, but not sinusoidal ECs maintain HSCs by secreting SCF. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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