| Autor: |
Yajuan Li, Xianwei Hu, Youhui Tu, Tao Wu, Bo Wang, Huan Ma, Weihong Zeng, Dan Zhao, Hylemariam Mihiretie Mengist, Arnaud John Kombe Kombe, Meijuan Zheng, Yuanhong Xu, Tengchuan Jin |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Frontiers in Public Health, Vol 8 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2296-2565 |
| DOI: |
10.3389/fpubh.2020.00339 |
| Popis: |
SARS-CoV-2 outbreak has attracted global attention. Verifying the presence of viral RNA is the gold standard for the diagnosis of COVID-19. However, RT-qPCR diagnosis often fails to catch infected patients, because of inconsistent swab sample collection. Here we report a case that showed 5 consecutive negative and 1 low-viral- dose RT-qPCR results during illness spanning over 20 days. Clinical symptoms suggest SARS-CoV-2 infection with typical ground glass like a lung in computed tomography. SARS-CoV-2 infection was serologically confirmed by the presence of anti-SARS-CoV-2 specific antibodies in patients' serum. Finally, a high level of protective IgG was produced after the patient recovered. Surprisingly, as a barber and a housewife staying at home for the first 2 weeks after the onset of illness, none of the close contacts were infected, showing a case of low viral load and low infectivity in this patient. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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