Prognostic scores for predicting clinical outcomes in upper gastrointestinal bleeding

Autor: Gaurav Khatana, Sunil Kumar K, Sandesh Kolassery, Saji Sebastian, Deni Joseph, Ramu Muraleedharanpillai, Tony Joseph, Nithya V, Lal Krishna Unnikrishnan, Gino Rony
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Egyptian Liver Journal, Vol 14, Iss 1, Pp 1-17 (2024)
Druh dokumentu: article
ISSN: 2090-6226
DOI: 10.1186/s43066-024-00357-0
Popis: Abstract Background and aims This study aimed to determine the performance of AIMS65, Rockall score, and Glasgow-Blatchford score (GBS) in patients presenting with upper gastrointestinal bleeding (UGIB) and to compare results between patients with nonvariceal UGIB (NVUGIB) and variceal UGIB (VUGIB). Methods We conducted a single-center prospective cohort study between December 2021 and December 2022. A total of 400 patients who met the inclusion criteria were included in the study, out of which 232 patients (58%) had NVUGIB and 168 patients (42%) had VUGIB. Receiver operating characteristic curve analysis was performed for all outcomes for comparison. Results Of the total of 400 patients with UGIB, 232 patients (58%) had NVUGIB, and 168 patients (42%) had VUGIB. The present study showed that GBS (AUROC 0.729, 95% CI: 0.598–0.859, p = 0.001) and RS (AUROC 0.693, 95% CI: 0.579–0.807, p = 0.005) but not AIMS65 (AUROC, 0.545, 95% CI: 0.412–0.679, p = 0.500) predicted in-hospital and overall 6-week mortality in patients with UGIB. All the three scores predicted need for blood transfusion and poor composite outcomes (p 0.05). Conclusions GBS and RS were superior to AIMS65 in predicted in-hospital and overall 6-week mortality in all the three categories: OUGIB, NVUGIB, and VUGIB patients.
Databáze: Directory of Open Access Journals
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