The influence of genetic factors on the effectiveness, safety and tolerability of antiretroviral therapy in patients with hiv infection

Autor: V. G. Kanestri, V. I. Shakhgildyan, A. V. Kravchenko, D. S. Konnov, A. A. Popova
Jazyk: ruština
Rok vydání: 2021
Předmět:
Zdroj: Журнал инфектологии, Vol 13, Iss 1, Pp 21-28 (2021)
Druh dokumentu: article
ISSN: 2072-6732
DOI: 10.22625/2072-6732-2021-13-1-21-28
Popis: This article provides an overview of the existing literature on the pharmacogenetic determinants of exposure and toxicity of antiretroviral drugs, as well as on genetic markers associated with the rate of disease progression. In addition, this article looks at current clinical opportunities as well as genetics in HIV drug development. Large-scale, integrated approaches to the genome are expected to significantly change the knowledge landscape in the future.
Databáze: Directory of Open Access Journals