Transformation of a prostatic adenocarcinoma into squamous cell carcinoma after luteinizing hormone-releasing hormone agonist and radiotherapy treatment

Autor: Hamza Ichaoui, Sonia Ben Nasr, Faten Gargouri, Aref Zribi, Amine Hermi, Sana Fendri, Mehdi Balti, Jihen Ayari, Ramzi Khiari, Issam Msakni, Nada Mansouri, Samir Ghozzi, Abderrazek Haddaoui
Jazyk: English<br />French
Rok vydání: 2019
Předmět:
Zdroj: The Pan African Medical Journal, Vol 34, Iss 125 (2019)
Druh dokumentu: article
ISSN: 1937-8688
DOI: 10.11604/pamj.2019.34.125.19421
Popis: Squamous cell carcinoma of the prostate is rare and represents 0.5% to 1% of prostatic carcinomas. Transformation of prostatic adenocarcinoma into squamous cell carcinoma after LH-RH agonist intake has been reported in only 8 cases in the literature. To our knowledge, our case is the second pure squamous cell carcinoma observed after hormonotherapy and radiotherapy. We reported a case of a patient with prostatic adenocarcinoma treated by radical prostatectomy followed by radiotherapy. Eleven years later, he had a vesical recurrence of prostatic adenocarcinoma. Our patient had an endoscopic resection followed by injections of Triptorelin. Six months later, he developed a local recurrence of a squamous cell carcinoma.
Databáze: Directory of Open Access Journals