Impact of 10-valent pneumococcal conjugate vaccine on pneumococcal meningitis in children up to two years of age in Brazil
| Autor: | Indianara Maria Grando, Camile de Moraes, Brendan Flannery, Walter Massa Ramalho, Marco Aurélio P. Horta, Diana Lucia Moura Pinho, Gilmara Lima Nascimento |
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| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Cadernos de Saúde Pública, Vol 31, Iss 2, Pp 276-284 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1678-4464 0102-311X |
| DOI: | 10.1590/0102-311X00169913 |
| Popis: | The objective of this study was to analyze the impact of vaccination against Streptococcus pneumoniae on the morbidity and mortality from pneumococcal meningitis in children ≤ 2 years in Brazil, from 2007 to 2012. This is a descriptive study and ecological analysis using data from the Information System on Notifiable Diseases. Pre-vaccination (2007-2009) and post-vaccination (2011-2012) periods were defined to compare incidence rates and mortality. A total of 1,311 cases and 430 deaths were reported during the study period. Incidence decreased from 3.70/100,000 in 2007 to 1.84/100,000 in 2012, and mortality decreased from 1.30/100,000 to 0.40/100,000, or 50% and 69% respectively, with the greatest impact in the 6-11 month age group. This decrease in Pneumococcal meningitis morbidity and mortality rates two years after introduction of the 10-valent pneumococcal conjugate vaccine suggests its effectiveness. |
| Databáze: | Directory of Open Access Journals |
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