Low-grade malignant myoepithelioma arising in a pleomorphic adenoma: a rare case
| Autor: | Emad Raddaoui, Ahmed S. Al-Hujaily, Saleh F. Al-Dhahri |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Annals of Saudi Medicine, Vol 32, Iss 2, Pp 209-212 (2012) |
| Druh dokumentu: | article |
| ISSN: | 0256-4947 0975-4466 |
| DOI: | 10.5144/0256-4947.2012.209 |
| Popis: | Malignant myoepithelioma is a very rare salivary gland tumor that can arise de novo or within a pre-existing pleomorphic adenoma. We report a case of malignant myoepithelioma most probably arising in a pre-existing pleomorphic adenoma of the left parotid gland. The patient was a 60-year-old man who presented with a multinodular mass lesion over left side of the face and neck. He had undergone removal of a pleomorphic adenoma of the left parotid gland twice (8 and 22 years ago). Histological examination showed locally concentrated highly invasive myoepithelial cells with bland-looking morphology and no evidence of mitosis or necrosis. Immunohistochemistry confirmed the myoepithelial differentiation (S-100+, SMA+) and a low Ki-67 labeling index (< 5%). |
| Databáze: | Directory of Open Access Journals |
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