Morbid obesity impacts mortality among inpatients with type a aortic dissection: an analysis of the national inpatient sample

Autor: Xiao Xu, Renqi Yin, Kangkang Zhi, Yingyi Qin, Boxiang Tu, Shengyong Wu, Ziwei Dong, Dongxu Liu, Jia He
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Cardiothoracic Surgery, Vol 18, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 1749-8090
DOI: 10.1186/s13019-022-02080-6
Popis: Abstract Background Stanford type A aortic dissection (T(A)AD) is one of the most dangerous cardiovascular diseases and morbid obesity is associated with the prognosis of many cardiovascular diseases. The aim of this study is to investigate the impact of morbid obesity on in-hospital mortality, total hospital costs and discover the prevalence of morbid obesity among inpatients with T(A)AD. Methods Patients with a primary diagnosis of T(A)AD were identified from the National Inpatient Sample database (NIS) from 2008 to 2017. These patients were categorized into non-obesity, obesity and morbid obesity. Multivariable regression models were utilized to assess the association between obesity/morbid obesity and in-hospital mortality, total cost and other clinical factors. The temporal trend in prevalence of obesity/morbid obesity in T(A)ADs and the trend of in-hospital mortality among different weight categories were also explored. Results From the NIS database 8489 T(A)AD inpatients were identified, of which 7230 (85.2%) patients were non-obese, 822 (9.7%) were obese and 437 (5.1%) were morbid obese. Morbid obesity was associated with increased risk of in-hospital mortality (odds ratio [OR] 1.39; 95% confidence interval [CI] 1.03–1.86), 8% higher total cost compared with the non-obese patients. From 2008 to 2017, the rate of obesity and morbid obesity in patients with T(A)AD have significantly increased from 7.36 to 11.33% (P
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