Association of lifestyle factors and inflammation with sarcopenic obesity: data from the PREDIMED‐Plus trial

Autor: Itziar Abete, Jadwiga Konieczna, M. Angeles Zulet, Aina M. Galmés‐Panades, Idoia Ibero‐Baraibar, Nancy Babio, Ramón Estruch, Josep Vidal, Estefanía Toledo, Cristina Razquin, Rafael Bartolomé, Andrés Díaz‐Lopez, Miquel Fiol, Rosa Casas, Josep Vera, Pilar Buil‐Cosiales, Xavier Pintó, Emili Corbella, Maria Puy Portillo, Jose Antonio dePaz, Vicente Martín, Lidia Daimiel, Albert Goday, Nuria Rosique‐Esteban, Jordi Salas‐Salvadó, Dora Romaguera, J. Alfredo Martínez, on behalf of PREDIMED‐PLUS Investigators
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 5, Pp 974-984 (2019)
Druh dokumentu: article
ISSN: 2190-6009
2190-5991
DOI: 10.1002/jcsm.12442
Popis: Abstract Background Sarcopenia is a progressive age‐related skeletal muscle disorder associated with increased likelihood of adverse outcomes. Muscle wasting is often accompanied by an increase in body fat, leading to ‘sarcopenic obesity’. The aim of the present study was to analyse the association of lifestyle variables such as diet, dietary components, physical activity (PA), body composition, and inflammatory markers, with the risk of sarcopenic obesity. Methods A cross‐sectional analysis based on baseline data from the PREDIMED‐Plus study was performed. A total of 1535 participants (48% women) with overweight/obesity (body mass index: 32.5 ± 3.3 kg/m2; age: 65.2 ± 4.9 years old) and metabolic syndrome were categorized according to sex‐specific tertiles (T) of the sarcopenic index (SI) as assessed by dual‐energy X‐ray absorptiometry scanning. Anthropometrical measurements, biochemical markers, dietary intake, and PA information were collected. Linear regression analyses were carried out to evaluate the association between variables. Results Subjects in the first SI tertile were older, less physically active, showed higher frequency of abdominal obesity and diabetes, and consumed higher saturated fat and less vitamin C than subjects from the other two tertiles (all P
Databáze: Directory of Open Access Journals
Externí odkaz: